Strategic Initiative

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DARPA and JPEO Award Contract to SmartPharm, a Subsidiary of Sorrento (SRNE), for Development of Rapid Countermeasure Against COVID-19 Using Gene-Encoded Neutralizing Antibodies

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SRNE

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Additional Information

Additional Relevant Details
  • Initial funding of up to $34 million for the project “Gene Mabs: A Scalable, Economic, Gene-Encoded Protective Antibody Platform Against Coronavirus” (HR0011-21-9-0015) to support the development of an STI-2020-encoded Gene MAbTM through Phase 2 clinical studies.
  • STI-2020-encoded Gene MAb is in development for intramuscular injection against the SARS-CoV-2 virus and its variant strains to produce potent STI-2020 nAbs in the body.
  • STI-2020-encoded Gene MAb products can potentially be stored at refrigerator temperatures, avoiding some of the cold chain management challenges associated with the deployment of COVID-19 vaccines currently in development.  
  • Sorrento has a cGMP facility in place to meet initial production demand and Sorrento expects that STI-2020-encoded Gene MAb can be produced in large quantity to meet potentially high demand.
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Slingshot Insights Explained
Strategic Initiative Date
Announcement Date:
Nov 27, 2020
Projected Implementation:
Q4, 2020
Relevance Tracked Until:
Q1, 2021
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Related Keywords Gene-encoded Neutralizing Antibodies, Sti-2020