Expert Interview
Digging into the opioid reversal market and potential use of OPNT003
Ticker(s): OPNT, INVVYInstitution: Ohio Department of Public Safety
- State Medical Director for the Ohio Department of Public Safety, Division of EMS, board-certified emergency physician at Cleveland Clinic Akron General Medical Center and an associate professor of emergency medicine at Northeast Ohio Medical University
- Co-principal investigator for the National Association of State EMS Officials (NASEMSO) National Model EMS Clinical Guidelines project.
- Makes recommendations on behalf of the Ohio Department of Public Safety to comptrollers as to how much naloxone should be purchased in bulk and creates the naloxone modules, trainings and presentations
- Nationally recognized expert in opioid crisis and treatment; serves on the Department of Homeland Security Science & Technology Directorate’s First Responder Resource Group and the EMS Support Team of the Department of Homeland Security/ Federal Emergency Management Agency.
Please tell us about your clinical experience. How many patients with opioid overdose do you see yearly? What is the most effective treatment for reversing the risk of death and disabilities associated with overdose?
Which are the most common purchased opioid reversal agents and why?
Have you used Opiant’s NARCAN - Nasal Spray in emergency situations, since its approval for opioid overdose?
Added By: c_adminThe company cites nasal sprays have an advantage in more rapid absorption and higher plasma concentrations versus a nalmefene intramuscular injection. How much has standard of treatment changed because of this?
What’s been the response to the increase in opioid overdoses in the past years, with the introduction of synthetic opioids like fentanyl?
Added By: c_adminOpinant is testing OPNT003 with nasal naloxone in reversing the respiratory depression produced by the synthetic opioid, remifentanil. Could the potential efficacy also apply to other opioid drug overdoses?
How likely would you be to prescribe OPNT003 in the future, what’s its potential to become a new standard of care in the treatment of opioid overdose?
Added By: c_adminAre You Interested In These Questions?
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